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The Complete Stimulant Encyclopedia

100+ entries on stimulants, nootropics, and cognitive enhancers. Mechanisms, dosing, stacking, safety โ€” everything you need to know.

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Half-Life Calculator

Half-life is how long your body needs to clear half of a dose. Enter any dose and half-life to see how much is left later, and how long until it is effectively gone.

The maths is exact: remaining equals dose multiplied by 0.5 raised to the power of time divided by half-life. The listed half-lives are typical adult averages from published pharmacokinetics and vary widely between people; caffeine alone ranges from roughly 2 to 9 hours. Educational information, not medical advice.

Pharmacokinetics

Half-Lives, Side by Side

Half-life explains why one stimulant clears before lunch and another is still with you at bedtime. Five half-lives is the usual rule of thumb for a compound being effectively gone.

Bar chart of half-life for common compounds: theobromine 7 hours, caffeine 5 hours, nicotine 2 hours, L-theanine 1.2 hours
Typical adult half-lives for four common compounds, in hours.

Typical adult averages from published pharmacokinetics; individual values vary widely, and caffeine alone ranges from roughly 2 to 9 hours. Theobromine is the long-lasting stimulant in chocolate.

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